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Severe community-acquired pneumonia (SCAP) remains a leading cause of morbidity and mortality worldwide. Identifying the optimal antibiotic regimen for treating SCAP is crucial for improving patient outcomes.
Cigarette smoking is an important risk factor in lung cancer development. As a class of regulatory RNAs, microRNAs (miRs) participate in various biological processes. In the present study, we searched for the ...
To investigate the incidence and severity of symptoms in postoperative non-small-cell lung cancer patients undergoing thoracoscopic surgery, construct a symptom network, and analyze centrality indicators of th...
After transbronchial biopsy with flexible bronchoscopy, pneumonia sometimes occurs as a complication. The goal of our study was to determine whether irrigation of the working channel before diagnostic procedur...
To probe the diagnostic value of direct eosinophils (EOS) count and vascular endothelial growth factor (VEGF) in bronchial asthma (BA) and their correlation with inflammatory factors and lung function indicators.
Lymphatic malformations (LMs) involving the thorax are rare, with limited clinical understanding. We aimed to summarize the classification, clinical features, treatment, and prognosis of thoracic LMs, and to i...
Severe asthma affects 3.6% of the asthma population, in which patients are uncontrolled despite optimal drug therapy and management of treatable traits. These patients are eligible for treatment with biologica...
Peak expiratory flow (PEF) measurement is useful for detecting moderate and severe chronic obstructive pulmonary disease (COPD). We aimed to validate its combined effectiveness with a questionnaire and to dete...
Non-human immunodeficiency virus (HIV) immunocompromised patients with Pneumocystis jirovecii pneumonia (PJP) face rapid progression and high mortality, necessitating a predictive model to identify patients at ri...
Tracheal rupture is a rare but serious complication associated with tracheal intubation, often presenting with clinical manifestations such as subcutaneous emphysema, mediastinal emphysema, and pneumothorax. P...
Pneumoconiosis is still the most common occupational disease worldwide. The aim of the study was to evaluate the risk factors affecting survival in patients with pneumoconiosis who were followed up in occupati...
Monitoring COPD patients: systemic and bronchial eosinophilic inflammation in a 2-year follow-up" by Pignatti et al. provides valuable insights about changes in blood and sputum eosinophils in mild to moderate...
Chronic cough is associated with reduced mental and physical health and increased health care resource use. The lack of nationwide data on chronic cough hinders our understanding of the prevalence, demographic...
The aim of this study is to explore the mechanism of the role of kinesiophobia in patients with chronic obstructive pulmonary disease (COPD), to construct a structural equation model of the factors influencing...
Chronic respiratory diseases (CRD) often coexist with other non-communicable diseases (NCD) and are responsible for nearly three-quarters of all deaths in low- and middle-income countries (LMIC). People living...
Pulmonary hypertension (PH) complicates the course of patients with interstitial lung disease (ILD) in 30–55% of cases and is associated with increased morbidity and mortality. The optimal timing of diagnostic...
With the development and market launch of several new domestic lung diffusing capacity testing instruments, the clinical reliability of the MeHow MeAir 9000 spirometer, featuring a novel turning valve structur...
The role of chronic inflammation in non-idiopathic pulmonary fibrosis fibrotic interstitial lung disease (non-IPF f-ILD) remains unclear, with varied responses to anti-inflammatory or immunosuppressive therapy...
Access to spirometry remains limited due to the expense and inconvenience of stationary laboratory spirometers, which may compromise the diagnosis and management of chronic respiratory diseases (CRDs), such as...
Sarcoidosis is a complex multisystemic disease with a wide range of clinical manifestations. Its severity and evolution are highly variable and the prognostic utility of paraclinical markers is debated. We ana...
Empyema necessitans is an uncommon complication of an empyema, where pus in the pleural cavity extends into the chest wall. Both medical and surgical management are required. Here we have identified the first ...
This study aims to investigate the correlations between oxidized lipoproteins, specifically oxidized low-density lipoprotein (oxLDL) and oxidized high-density lipoprotein (oxHDL), and the comorbidities of T2DM...
Previous studies have shown that the lactate/albumin ratio (LAR) can be a prognostic biomarker in intensive care unit (ICU) patients. However, the usefulness of LAR in predicting mortality and guiding intensiv...
Chronic Obstructive Pulmonary Disease (COPD) and sarcopenia (SAR) are major public health problems in aging societies, as they share common pathophysiological mechanisms and are associated with serious health ...
The optimal duration of steroid therapy for patients with COVID-19 remains unclear. This study compared clinical outcomes between early steroid withdrawal (EW; ≤10 days) and prolonged steroid tapering (PT; >10...
The antifibrotic therapies, pirfenidone and nintedanib, have been approved since 2014 for idiopathic pulmonary fibrosis (IPF), but in the United States only a quarter of people living with IPF have ever been e...
To evaluate the effectiveness of various nutritional supplements as interventions for patients with Chronic Obstructive Pulmonary Disease (COPD) using network meta-analysis.
Programmed death-ligand 1 (PD-L1) expression is a key biomarker for predicting the efficacy of immune checkpoint inhibitors (ICIs). With the successful application of perioperative immunotherapy, understanding...
This study investigates the impact of obesity on impulse oscillometry (IOS) parameters in individuals with asthma, chronic obstructive pulmonary disease (COPD), other lung diseases, and non-respiratory conditi...
The Pulmonary Arterial Hypertension-Symptoms and Impact (PAH-SYMPACT) questionnaire is a patient-reported outcome measure designed to assess pulmonary arterial hypertension (PAH) symptoms and impacts in clinic...
This study aimed to assess the nutritional status of individuals with severe asthma and to determine how dietary antioxidant (AO) intake influences the disease prognosis and plasma total antioxidant status (TAS).
This study utilizes electrical impedance tomography (EIT) to explore spatial–temporal heterogeneity in regional lung function among patients with chronic obstructive lung disease (COPD), preserved ratio impair...
Pneumonia represents a significant global health burden with high morbidity and mortality rates, despite advances in therapeutic and preventive strategies. Airway clearance techniques (ACT), including High-Fre...
As a cardiovascular health (CVH) assessment tool, Life’s Crucial 9 (LC9) is often associated with diverse chronic health indicators. However, no study has yet explored the association of LC9 with multifactoria...
Cystic fibrosis (CF) is a genetic disorder characterized by progressive lung disease and extra-pulmonary manifestations with notable sex disparities in disease outcomes. In this review we summarize the underly...
The original article was published in BMC Pulmonary Medicine 2025 25:155
Severe community-acquired pneumonia (CAP) is a potentially fatal pulmonary disease. Although studies have investigated the efficacy and safety of corticosteroids for severe CAP, the results remain inconsistent...
Clinical observational studies have shown an association between educational attainment and a lower incidence of Chronic Obstructive Pulmonary Disease (COPD). However, strong evidence for a causal relationship...
The folic acid is used as an adjuvant dietary supplement in cancer treatment, but its potential benefits or adverse effects in lung cancer (LC) management remain unclear. This study aimed to examine the relati...
The treatment plan and process for acute pneumonia caused by Tropheryma whipplei have not been clearly defined. The study aimed to conduct a retrospective analysis of the treatment for patients with acute pneu...
Chronic obstructive pulmonary disease (COPD) involves inflammation as a key factor influencing its pathology and progression. This meta-analysis sought to assess the prognostic importance of the neutrophil-to-...
Surgery resection would improve idiopathic pulmonary fibrosis (IPF) patients with early-stage lung cancer (LC). However, most associated studies were published from surgeons. Interstitial lung disease (ILD) ph...
Bronchial asthma is a major global health concern among children. It poses a significant global public challenge, causing around 22.8 million years of life lost to disability and 495,100 asthma-related deaths.
Respiratory sequelae, induced by lung injury, reduced muscle strength, and nutritional disturbance, are common in hospitalized patients with coronavirus disease 2019 (COVID-19). Therefore, optimal treatment is...
Chylothorax is defined by the accumulation of chyle in the pleural space, characterized by triglyceride levels exceeding 110 milligrams per deciliter. The clinical presentation of chylothorax varies depending ...
Early in the pandemic, corticosteroids became standard treatment for patients with critical COVID-19 infections. This study aimed to investigate the possible long-term pulmonary consequences after corticostero...
Aluminum induced lung disease is associated with pulmonary fibrosis, granulomatous pneumonia, and pulmonary alveolar proteinosis. Recognizing aluminum pneumoconiosis remains important as demand for aluminum pr...
Asthma is a prevalent noncommunicable disease worldwide, imposing significant burdens and diminishing the quality of life for those affected. Pay-for-Performance (P4P) programs are reimbursement models that of...
Percutaneous dilatational tracheostomy (PDT) is a common procedure for mechanically ventilated patients in the intensive care unit (ICU). This study compared the real-time ultrasound-guided PDT using a larynge...
The use of biological agents in various diseases in children has been increasing and the risk of tuberculosis (TB) increases with them. We aimed to investigate the role of biological agents in children diagnos...
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